Quick USMLE Review Notes for Step 1:

In USMLE exams, we usually get a definite idea after reading question that these 3 out of 5 are
wrong choices and we always stuck with two choices in deciding which one is the correct
answer. That's why I have combined so many confusing things in my notes which you
will find in your 5 option on exam. I have also pointed out CLUES in BOLD to identify right
choices. This is the reason why I am able to sell over 250 notes with 100% positive feedbacks
with lots of good comments!!!

These notes helped me to get a score of 239/99

Few Examples: [Click on download on the right top corner to view sample of my USMLE notes / click on Home Page on the right top corner to visit my website.]

Abruptio Placenta: painful bleeding, maternal hypertension or cocaine abuse
Placenta Previa: painless bleeding, placenta implantation over cervical os

Rheumatic fever: Type-2 HS (Hyper Sensitivity)       
Rheumatoid arthritis: Type-3 HS

Carbomyl phosphate in cytoplasm: pyrimidine synthesis
Carbomyl phosphate in mitochondria: urea cycle [both are different enzymes with similar name]

Thiazide Diuretics: used in renal stone (hyper calciurea)
Loop Diuretics: used in hyper calcemia

Antibody Dependent Cellular Cytotoxicity (ADCC): IgG + NK cells - use CD 16 molecule
(Fc receptor) to identify target cells. (NOT CD 56)
NK cell mediated Cytotoxicity: CD 56 (No antibody involve. e.g. - lysis of infected RBCs)

de Quarian thyroiditis: (subacute granulomatous): painful, mild hyperthyroidism
Subacute Lymphocytic thyroiditis: painless, mild hyperthyroidism

Berger's disease: hematuria following URTI, IgA deposition in mesangium
Buerger's disease: (thromboangitis obliterates) - Male smoking cigarettes, involvement of toes

Congenital inguinal hernia: total failure of processus vaginalis to fuse
Hydrocele of spermatic cord: incomplete fusion of processus vaginalis

Pericentral vein zone (zone 3) in liver contains P450 oxidase enzyme system & is most
sensitive to Ischemic injury
Periportal zone (zone 1) in liver is the most sensitive to toxic injury

Pemphigus vulgaris: IgG against desmosomes (intracellular atttachment), (+) Nikolsky sign,
oral lesion
Bullous Pemphigoid: IgG against basement membrane, (-) Nikolsky sign

Cortical necrosis of both kidney sparing medulla - DIC
Sickle cell anemia - Affect medulla most severly - can cause papillary necrosis

Hypokalamia - "U" wave on EKG       Hyperkalamia - peaked T wave on EKG


My Step 1 notes cover following subjects now :

Microbiology, Immunology, Pathology, Pharmacology, Anatomy, Physiology, Neuroscience, Behavior Science, Biochemistry, Cell Biology, Genetics, Histology, Buzz Words



Comment I received about my notes:

Thanks a bunch .. these look awesome!  Your suggestions are really helpful
as well. . I really appreciate it.  I'm using first aid,the kaplan 7 book
series w/ videos + med essentials, and qbook/ qbank/ pretest/usmle world for
step 1 study over about 3 months.  These notes look great, highlighting main
points.  Thanks for adding the neuro/ physiology as well . . I've been using
BRS costanzo w/ kaplan videos but these are great high yield facts you're
providing, and your handwriting is very easy to read.  Best of luck to you
in your work/ residency!

Delivery of My notes:

You will be able to download my high yield notes immediately. After you complete
transaction, do NOT close browser but click on "Complete Purchase". It will take you to
the "thank you" page where you will be able to download these notes immediately.